Nonprofit jobs in St. Louis, Missouri
Updated November 3, 2026
ExecSearches has 5 senior nonprofit and public-sector openings in the St. Louis metro, Missouri and Illinois sides right now. This page reads our job board each time it loads, so new St. Louis postings appear here the moment they are approved, and the page stays up with local facts even when no St. Louis job is open.
Current openings in the St. Louis area
Covers the St. Louis metro, Missouri and Illinois sides.
Executive Director
America's Watershed Initiative
St. Louis · Remote-friendly · Posted November 3, 2026
Sr. Director, Institutional Compliance, Accessibility & Title IX Coordination
Webster University
St. Louis · Posted October 31, 2026
Executive Director, Interdisciplinary Center for Autism Services
Saint Louis University
Saint Louis · Posted October 27, 2026
Executive Director, Leadership, Talent & Organizational Development
Washington University in St. Louis
Saint Louis · Posted October 23, 2026
Senior Director, Corporate Relations- St Louis, MO
American Cancer Society
Saint Louis · Posted October 23, 2026
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More openings in Missouri
Senior Impact Officer Strategic Initiatives
Ewing Marion Kauffman Foundation
Kansas City · Posted October 28, 2026
Chief Executive Officer
Life Unlimited
North Kansas City · Posted October 9, 2026
Mo P&A Executive Director
Missouri Protection and Advocacy Services
Jefferson City · Posted October 8, 2026
Director Risk Management
Saint Luke's Health System
Posted August 25, 2026
Health System Privacy Officer
University of Missouri Health Care
Columbia · Posted August 15, 2026
All nonprofit jobs in Missouri
St. Louis at a glance
| City population | 278,144 St. Louis city, July 1, 2025 estimate. Source: U.S. Census Bureau, Vintage 2025 population estimates |
|---|---|
| Metro population | 2,814,421 St. Louis, MO-IL, July 1, 2025. Source: U.S. Census Bureau, Vintage 2025 metro estimates |
| Median household income | $53,962 St. Louis city $53,962; St. Louis County $84,109 (2024). Source: U.S. Census Bureau, Small Area Income and Poverty Estimates (SAIPE) |
| Poverty rate | 21.8% all ages, St. Louis city 21.8%; St. Louis County 9.8% (2024). Source: U.S. Census Bureau, SAIPE |
| 501(c)(3) organizations | 8,493 with a St. Louis mailing address. Source: IRS Exempt Organizations Business Master File, October 2026 release |
| Price level | 95.1 St. Louis, MO-IL metro, U.S. = 100, 2024 (Missouri 90.8). Source: U.S. Bureau of Economic Analysis, Regional Price Parities |
| Unemployment rate | 3.4% metro, September 2026, preliminary, not seasonally adjusted. Source: U.S. Bureau of Labor Statistics, Local Area Unemployment Statistics |
What nonprofit leaders earn in St. Louis
IRS Form 990 filings put median chief executive pay at St. Louis-area community nonprofits at about $125,000 for organizations with $1 million to $10 million in revenue, and about $233,000 above $10 million (fiscal years 2023 to 2026). Prices in the St. Louis metro run about 5% below the national average (95.1 on the U.S. Bureau of Economic Analysis 2024 Regional Price Parities, U.S. = 100; Missouri as a whole was 90.8).
Major nonprofit employers in St. Louis
- BJC HealthCare: The region's largest health system. BJC careers
- Washington University in St. Louis: Private research university and medical school. WashU jobs
- Mercy: Catholic health system headquartered in the St. Louis area. Mercy careers
- SSM Health: Catholic health system based in St. Louis. SSM Health careers
- Donald Danforth Plant Science Center: Independent plant science research institute. Danforth Center careers
- United Way of Greater St. Louis: The regional United Way, serving Missouri and Illinois. United Way of Greater St. Louis careers
Our St. Louis guide
Our St. Louis guide covers what nonprofit leaders earn there (IRS Form 990 pay tables by organization size), the major employers in health care, higher education and plant science, the search firms that recruit in the region, and how the cost of living compares.
Frequently asked questions
How many nonprofit executive jobs are open in St. Louis right now?
The count at the top of this page is live: it reads the ExecSearches job board each time the page loads and lists every open senior role in the St. Louis metro, Missouri and Illinois sides.
What does a nonprofit executive director earn in St. Louis?
IRS Form 990 filings put median chief executive pay at St. Louis-area community nonprofits at about $125,000 for organizations with $1 million to $10 million in revenue, and about $233,000 above $10 million (fiscal years 2023 to 2026).
How does the cost of living in St. Louis affect nonprofit pay?
Prices in the St. Louis metro run about 5% below the national average (95.1 on the U.S. Bureau of Economic Analysis 2024 Regional Price Parities, U.S. = 100; Missouri as a whole was 90.8).
How do I hear about new St. Louis nonprofit jobs?
Set up a free ExecSearches job alert for Missouri and you get an email when a matching role posts. ExecSearches does not sell job seeker data.
What does the ExecSearches St. Louis guide cover?
Our St. Louis guide covers what nonprofit leaders earn there (IRS Form 990 pay tables by organization size), the major employers in health care, higher education and plant science, the search firms that recruit in the region, and how the cost of living compares.